Vaccine Types

Characteristics

Immune Aspects

Main Disadvantages

Attenuated Vaccines

Replicative live vaccine

TCD8+ cells activation

Potencial reversion of pathogenicity

Inactivated Vaccines

Inactive vaccines

B cells activation

Poor induction of T-cell response

Subunit Vaccines

Antigens from pathogens

TCD8+ and B cells activation

Immunogen preparation

Toxoid

Inactivated toxin

B cells activation

Transitory effect

Vectored Vaccines

Recombinant live vaccine

TCD8+ and B cells activation

Potencial of adverse effects

DNA Vaccine

Recombinant plasmid expressing antigen of interest

TCD8+ and B cells activation

Less efficient induction of antibody response